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De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

Adult mitotic tissues like the intestine, skin, and blood undergo constant turnover throughout the life of an organism. Knowing the identity of the stem cell is crucial to understanding tissue homeostasis and its aberrations upon disease. Here we present a computational method for the derivation of...

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Detalles Bibliográficos
Autores principales: Grün, Dominic, Muraro, Mauro J., Boisset, Jean-Charles, Wiebrands, Kay, Lyubimova, Anna, Dharmadhikari, Gitanjali, van den Born, Maaike, van Es, Johan, Jansen, Erik, Clevers, Hans, de Koning, Eelco J.P., van Oudenaarden, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985539/
https://www.ncbi.nlm.nih.gov/pubmed/27345837
http://dx.doi.org/10.1016/j.stem.2016.05.010