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5‐HT (2B) receptor antagonists attenuate myofibroblast differentiation and subsequent fibrotic responses in vitro and in vivo

Pulmonary fibrosis is characterized by excessive accumulation of connective tissue, along with activated extracellular matrix (ECM)‐producing cells, myofibroblasts. The pathological mechanisms are not well known, however serotonin (5‐HT) and 5‐HT class 2 (5‐HT (2)) receptors have been associated wit...

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Detalles Bibliográficos
Autores principales: Löfdahl, Anna, Rydell‐Törmänen, Kristina, Müller, Catharina, Martina Holst, C., Thiman, Lena, Ekström, Gunilla, Wenglén, Christina, Larsson‐Callerfelt, Anna‐Karin, Westergren‐Thorsson, Gunilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985542/
https://www.ncbi.nlm.nih.gov/pubmed/27482070
http://dx.doi.org/10.14814/phy2.12873