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Immobilization rapidly induces muscle insulin resistance together with the activation of MAPKs (JNK and p38) and impairment of AS160 phosphorylation

Acute short‐duration physical inactivity induces the development of insulin resistance for glucose uptake in skeletal muscle. We examined the possibility that inactivity rapidly induces muscle insulin resistance via the excessive activation of proinflammatory/stress pathways including those of IKK/I...

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Detalles Bibliográficos
Autores principales: Kawamoto, Emi, Koshinaka, Keiichi, Yoshimura, Tatsuhiko, Masuda, Hiroyuki, Kawanaka, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985544/
https://www.ncbi.nlm.nih.gov/pubmed/27482072
http://dx.doi.org/10.14814/phy2.12876