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Mycobacterial Acid Tolerance Enables Phagolysosomal Survival and Establishment of Tuberculous Infection In Vivo

The blockade of phagolysosomal fusion is considered a critical mycobacterial strategy to survive in macrophages. However, viable mycobacteria have been observed in phagolysosomes during infection of cultured macrophages, and mycobacteria have the virulence determinant MarP, which confers acid resist...

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Detalles Bibliográficos
Autores principales: Levitte, Steven, Adams, Kristin N., Berg, Russell D., Cosma, Christine L., Urdahl, Kevin B., Ramakrishnan, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985559/
https://www.ncbi.nlm.nih.gov/pubmed/27512905
http://dx.doi.org/10.1016/j.chom.2016.07.007