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Association between TLR4 and PTEN Involved in LPS-TLR4 Signaling Response

In this study, we explored the potential mechanisms of how PTEN regulating LPS induced TLR4 signaling pathway. The initial findings from ELISA demonstrate that PTEN influences TNF-α secretion by its lipid phosphatase activity. Subsequently, western blot, immunoprecipitation assay, and immunofluoresc...

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Detalles Bibliográficos
Autores principales: Yin, Huahua, Tan, Yan, Wu, Xiaofeng, Yan, Hong, Liu, Feng, Yao, Yuanzhang, Jiang, Jianxin, Wan, Qi, Li, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985570/
https://www.ncbi.nlm.nih.gov/pubmed/27563672
http://dx.doi.org/10.1155/2016/6083178