Cargando…

Understanding the molecular basis of substrate binding specificity of PTB domains

Protein-protein interactions mediated by phosphotyrosine binding (PTB) domains play a crucial role in various cellular processes. In order to understand the structural basis of substrate recognition by PTB domains, multiple explicit solvent atomistic simulations of 100ns duration have been carried o...

Descripción completa

Detalles Bibliográficos
Autores principales: Sain, Neetu, Tiwari, Garima, Mohanty, Debasisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985636/
https://www.ncbi.nlm.nih.gov/pubmed/27526776
http://dx.doi.org/10.1038/srep31418