iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers

Accurate prediction of the pathogenicity of genomic variants, especially nonsynonymous single nucleotide variants (nsSNVs), is essential in biomedical research and clinical genetics. Most current prediction methods build a generic classifier for all genes. However, different genes and gene families...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Wei, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985647/
https://www.ncbi.nlm.nih.gov/pubmed/27527004
http://dx.doi.org/10.1038/srep31321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985647/
https://www.ncbi.nlm.nih.gov/pubmed/27527004
http://dx.doi.org/10.1038/srep31321

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