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Integrated identification, qualification and quantification strategy for pharmacokinetic profile study of Guizhi Fuling capsule in healthy volunteers

Guizhi Fuling capsule (GZFL), a traditional Chinese medicine formulation, is widely used in China to relieve pain from dysmenorrhea and is now in a Phase II clinical trial in the USA. Due to the low exposure of the five main medicative ingredients (amygdalin, cinnamic acid, gallic acid, paeoniflorin...

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Detalles Bibliográficos
Autores principales: Zhong, Yun-Xi, Jin, Xiao-Liang, Gu, Shi-Yin, Peng, Ying, Zhang, Ke-Rong, Ou-Yang, Bing-Chen, Wang, Yu, Xiao, Wei, Wang, Zhen-Zhong, Aa, Ji-Ye, Wang, Guang-Ji, Sun, Jian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985661/
https://www.ncbi.nlm.nih.gov/pubmed/27527657
http://dx.doi.org/10.1038/srep31364