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Ribosome Subunit Stapling for Orthogonal Translation in E.  coli

The creation of orthogonal large and small ribosomal subunits, which interact with each other but not with endogenous ribosomal subunits, would extend our capacity to create new functions in the ribosome by making the large subunit evolvable. To this end, we rationally designed a ribosomal RNA that...

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Detalles Bibliográficos
Autores principales: Fried, Stephen D., Schmied, Wolfgang H., Uttamapinant, Chayasith, Chin, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY‐VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985662/
https://www.ncbi.nlm.nih.gov/pubmed/27570300
http://dx.doi.org/10.1002/ange.201506311