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A conditional likelihood is required to estimate the selection coefficient in ancient DNA
Time-series of allele frequencies are a useful and unique set of data to determine the strength of natural selection on the background of genetic drift. Technically, the selection coefficient is estimated by means of a likelihood function built under the hypothesis that the available trajectory span...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985692/ https://www.ncbi.nlm.nih.gov/pubmed/27527811 http://dx.doi.org/10.1038/srep31561 |