Enterovirus infection of human islets of Langerhans affects β-cell function resulting in disintegrated islets, decreased glucose stimulated insulin secretion and loss of Golgi structure

AIMS/HYPOTHESIS: In type 1 diabetes (T1D), most insulin-producing β cells are destroyed, but the trigger is unknown. One of the possible triggers is a virus infection and the aim of this study was to test if enterovirus infection affects glucose stimulated insulin secretion and the effect of virus r...

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Detalles Bibliográficos
Autores principales: Hodik, M, Skog, O, Lukinius, A, Isaza-Correa, J M, Kuipers, J, Giepmans, B N G, Frisk, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985798/
https://www.ncbi.nlm.nih.gov/pubmed/27547409
http://dx.doi.org/10.1136/bmjdrc-2015-000179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985798/
https://www.ncbi.nlm.nih.gov/pubmed/27547409
http://dx.doi.org/10.1136/bmjdrc-2015-000179

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