Structurally novel steroidal spirooxindole by241 potently inhibits tumor growth mainly through ROS-mediated mechanisms

Cancer cells always have increased ROS levels, thus making them more vulnerable to persistent endogenous oxidative stress. The biochemical difference between cancer and normal cells could be exploited to achieve selective cancer cell killing by exogenous ROS-producing agents. Herein we described a s...

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Detalles Bibliográficos
Autores principales: Shi, Xiao-Jing, Yu, Bin, Wang, Jun-Wei, Qi, Ping-Ping, Tang, Kai, Huang, Xin, Liu, Hong-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985843/
https://www.ncbi.nlm.nih.gov/pubmed/27527552
http://dx.doi.org/10.1038/srep31607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985843/
https://www.ncbi.nlm.nih.gov/pubmed/27527552
http://dx.doi.org/10.1038/srep31607

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