Cargando…

TNF activation of NF-κB is essential for development of single-positive thymocytes

NF-κB activation has been implicated at multiple stages of thymic development of T cells, during which it is thought to mediate developmental signals originating from the T cell receptor (TCR). However, the Card11–Bcl10–Malt1 (CBM) complex that is essential for TCR activation of NF-κB in peripheral...

Descripción completa

Detalles Bibliográficos
Autores principales: Webb, Louise V., Ley, Steven C., Seddon, Benedict
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986527/
https://www.ncbi.nlm.nih.gov/pubmed/27432943
http://dx.doi.org/10.1084/jem.20151604