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E3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor–mediated antifungal innate immunity

Activation of various C-type lectin receptors (CLRs) initiates potent proinflammatory responses against various microbial infections. However, how activated CLRs are negatively regulated remains unknown. In this study, we report that activation of CLRs Dectin-2 and Dectin-3 by fungi infections trigg...

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Detalles Bibliográficos
Autores principales: Zhu, Le-Le, Luo, Tian-Ming, Xu, Xia, Guo, Ya-Hui, Zhao, Xue-Qiang, Wang, Ting-Ting, Tang, Bing, Jiang, Yuan-Ying, Xu, Jin-Fu, Lin, Xin, Jia, Xin-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986534/
https://www.ncbi.nlm.nih.gov/pubmed/27432944
http://dx.doi.org/10.1084/jem.20151932