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E3 ubiquitin ligase Cbl-b negatively regulates C-type lectin receptor–mediated antifungal innate immunity
Activation of various C-type lectin receptors (CLRs) initiates potent proinflammatory responses against various microbial infections. However, how activated CLRs are negatively regulated remains unknown. In this study, we report that activation of CLRs Dectin-2 and Dectin-3 by fungi infections trigg...
Autores principales: | Zhu, Le-Le, Luo, Tian-Ming, Xu, Xia, Guo, Ya-Hui, Zhao, Xue-Qiang, Wang, Ting-Ting, Tang, Bing, Jiang, Yuan-Ying, Xu, Jin-Fu, Lin, Xin, Jia, Xin-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986534/ https://www.ncbi.nlm.nih.gov/pubmed/27432944 http://dx.doi.org/10.1084/jem.20151932 |
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