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Siglec-H protects from virus-triggered severe systemic autoimmunity

It is controversial whether virus infections can contribute to the development of autoimmune diseases. Type I interferons (IFNs) are critical antiviral cytokines during virus infections and have also been implicated in the pathogenesis of systemic lupus erythematosus. Type I IFN is mainly produced b...

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Detalles Bibliográficos
Autores principales: Schmitt, Heike, Sell, Sabrina, Koch, Julia, Seefried, Martina, Sonnewald, Sophia, Daniel, Christoph, Winkler, Thomas H., Nitschke, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986536/
https://www.ncbi.nlm.nih.gov/pubmed/27377589
http://dx.doi.org/10.1084/jem.20160189