Correlation of Cytochrome P450 Oxidoreductase Expression with the Expression of 10 Isoforms of Cytochrome P450 in Human Liver

Human cytochrome P450 oxidoreductase (POR) provides electrons for all microsomal cytochromes P450 (P450s) and plays an indispensable role in drug metabolism catalyzed by this family of enzymes. We evaluated 100 human liver samples and found that POR protein content varied 12.8-fold, from 12.59 to 16...

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Detalles Bibliográficos
Autores principales: Zhang, Hai-Feng, Li, Zhi-Hui, Liu, Jia-Yu, Liu, Ting-Ting, Wang, Ping, Fang, Yan, Zhou, Jun, Cui, Ming-Zhu, Gao, Na, Tian, Xin, Gao, Jie, Wen, Qiang, Jia, Lin-Jing, Qiao, Hai-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986620/
https://www.ncbi.nlm.nih.gov/pubmed/27271371
http://dx.doi.org/10.1124/dmd.116.069849

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986620/
https://www.ncbi.nlm.nih.gov/pubmed/27271371
http://dx.doi.org/10.1124/dmd.116.069849

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