Pigment epithelium-derived factor (PEDF) normalizes matrix defects in iPSCs derived from Osteogenesis imperfecta Type VI

Osteogenesis imperfecta (OI) Type VI is characterized by a defect in bone mineralization, which results in multiple fractures early in life. Null mutations in the PEDF gene, Serpinf1, are the cause of OI VI. Whether PEDF restoration in a murine model of OI Type VI could improve bone mass and functio...

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Detalles Bibliográficos
Autores principales: Belinsky, Glenn S., Ward, Leanne, Chung, Chuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Addendum
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986704/
https://www.ncbi.nlm.nih.gov/pubmed/27579219
http://dx.doi.org/10.1080/21675511.2016.1212150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986704/
https://www.ncbi.nlm.nih.gov/pubmed/27579219
http://dx.doi.org/10.1080/21675511.2016.1212150

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