Somatic Variants in the Human Lens Epithelium: A Preliminary Assessment

PURPOSE: We hypothesize that somatic mutations accumulate in cells of the human lens and may contribute to the development of cortical or posterior sub-capsular cataracts. Here, we used a Next-generation sequencing (NGS) strategy to screen for low-allelic frequency variants in DNA extracted from hum...

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Detalles Bibliográficos
Autores principales: Mesa, Rosana, Tyagi, Manoj, Harocopos, George, Vollman, David, Bassnett, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2016
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986767/
https://www.ncbi.nlm.nih.gov/pubmed/27537255
http://dx.doi.org/10.1167/iovs.16-19726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986767/
https://www.ncbi.nlm.nih.gov/pubmed/27537255
http://dx.doi.org/10.1167/iovs.16-19726

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