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The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface
The removal of the 5′ 7-methylguanosine mRNA cap structure (decapping) is a central step in the 5′–3′ mRNA degradation pathway and is performed by the Dcp1:Dcp2 decapping complex. The activity of this complex is tightly regulated to prevent premature degradation of the transcript. Here, we establish...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986892/ https://www.ncbi.nlm.nih.gov/pubmed/27354705 http://dx.doi.org/10.1261/rna.057315.116 |