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The RNA-binding profile of Acinus, a peripheral component of the exon junction complex, reveals its role in splicing regulation

Acinus (apoptotic chromatin condensation inducer in the nucleus) is an RNA-binding protein (RBP) originally identified for its role in apoptosis. It was later found to be an auxiliary component of the exon junction complex (EJC), which is deposited at exon junctions as a consequence of pre-mRNA spli...

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Detalles Bibliográficos
Autores principales: Rodor, Julie, Pan, Qun, Blencowe, Benjamin J., Eyras, Eduardo, Cáceres, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986896/
https://www.ncbi.nlm.nih.gov/pubmed/27365209
http://dx.doi.org/10.1261/rna.057158.116