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Nitric Oxide Synthase 1 Modulates Basal and β-Adrenergic-Stimulated Contractility by Rapid and Reversible Redox-Dependent S-Nitrosylation of the Heart

S-nitrosylation of several Ca(2+) regulating proteins in response to β-adrenergic stimulation was recently described in the heart; however the specific nitric oxide synthase (NOS) isoform and signaling pathways responsible for this modification have not been elucidated. NOS-1 activity increases inot...

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Detalles Bibliográficos
Autores principales: Vielma, Alejandra Z., León, Luisa, Fernández, Ignacio C., González, Daniel R., Boric, Mauricio P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986959/
https://www.ncbi.nlm.nih.gov/pubmed/27529477
http://dx.doi.org/10.1371/journal.pone.0160813