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Nitric Oxide Synthase 1 Modulates Basal and β-Adrenergic-Stimulated Contractility by Rapid and Reversible Redox-Dependent S-Nitrosylation of the Heart
S-nitrosylation of several Ca(2+) regulating proteins in response to β-adrenergic stimulation was recently described in the heart; however the specific nitric oxide synthase (NOS) isoform and signaling pathways responsible for this modification have not been elucidated. NOS-1 activity increases inot...
Autores principales: | Vielma, Alejandra Z., León, Luisa, Fernández, Ignacio C., González, Daniel R., Boric, Mauricio P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4986959/ https://www.ncbi.nlm.nih.gov/pubmed/27529477 http://dx.doi.org/10.1371/journal.pone.0160813 |
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