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Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

Circulating cell-free DNA (cfDNA) released from cancerous tissues has been found to harbor tumor-associated alterations and to represent the molecular composition of the tumor. Recent advances in technologies, especially in next-generation sequencing, enable the analysis of low amounts of cfDNA from...

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Detalles Bibliográficos
Autores principales: Dietz, Steffen, Schirmer, Uwe, Mercé, Clémentine, von Bubnoff, Nikolas, Dahl, Edgar, Meister, Michael, Muley, Thomas, Thomas, Michael, Sültmann, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987014/
https://www.ncbi.nlm.nih.gov/pubmed/27529345
http://dx.doi.org/10.1371/journal.pone.0161012