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Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients
Circulating cell-free DNA (cfDNA) released from cancerous tissues has been found to harbor tumor-associated alterations and to represent the molecular composition of the tumor. Recent advances in technologies, especially in next-generation sequencing, enable the analysis of low amounts of cfDNA from...
Autores principales: | Dietz, Steffen, Schirmer, Uwe, Mercé, Clémentine, von Bubnoff, Nikolas, Dahl, Edgar, Meister, Michael, Muley, Thomas, Thomas, Michael, Sültmann, Holger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987014/ https://www.ncbi.nlm.nih.gov/pubmed/27529345 http://dx.doi.org/10.1371/journal.pone.0161012 |
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