Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis

BACKGROUND: Chronic pain is highly prevalent and a significant source of disability, yet its genetic and environmental risk factors are poorly understood. Its relationship with major depressive disorder (MDD) is of particular importance. We sought to test the contribution of genetic factors and shar...

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Detalles Bibliográficos
Autores principales: McIntosh, Andrew M., Hall, Lynsey S., Zeng, Yanni, Adams, Mark J., Gibson, Jude, Wigmore, Eleanor, Hagenaars, Saskia P., Davies, Gail, Fernandez-Pujals, Ana Maria, Campbell, Archie I., Clarke, Toni-Kim, Hayward, Caroline, Haley, Chris S., Porteous, David J., Deary, Ian J., Smith, Daniel J., Nicholl, Barbara I., Hinds, David A., Jones, Amy V., Scollen, Serena, Meng, Weihua, Smith, Blair H., Hocking, Lynne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987025/
https://www.ncbi.nlm.nih.gov/pubmed/27529168
http://dx.doi.org/10.1371/journal.pmed.1002090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987025/
https://www.ncbi.nlm.nih.gov/pubmed/27529168
http://dx.doi.org/10.1371/journal.pmed.1002090

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