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Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription
Newly born cells either continue to proliferate or exit the cell division cycle. This decision involves delaying expression of Cyclin E that promotes DNA replication. ORC1, the Origin Recognition Complex (ORC) large subunit, is inherited into newly born cells after it binds to condensing chromosomes...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987141/ https://www.ncbi.nlm.nih.gov/pubmed/27458800 http://dx.doi.org/10.7554/eLife.12785 |