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Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity

Embryonic stem cells (ESCs) can self-renew or differentiate into any cell type, a phenomenon known as pluripotency. Distinct pluripotent states, termed naive and primed pluripotency, have been described. However, the mechanisms that control naive-primed pluripotent transition are poorly understood....

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Detalles Bibliográficos
Autores principales: Williams, Charles A.C., Fernandez-Alonso, Rosalia, Wang, Jinhua, Toth, Rachel, Gray, Nathanael S., Findlay, Greg M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987282/
https://www.ncbi.nlm.nih.gov/pubmed/27498864
http://dx.doi.org/10.1016/j.celrep.2016.07.033