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Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity
Embryonic stem cells (ESCs) can self-renew or differentiate into any cell type, a phenomenon known as pluripotency. Distinct pluripotent states, termed naive and primed pluripotency, have been described. However, the mechanisms that control naive-primed pluripotent transition are poorly understood....
Autores principales: | Williams, Charles A.C., Fernandez-Alonso, Rosalia, Wang, Jinhua, Toth, Rachel, Gray, Nathanael S., Findlay, Greg M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987282/ https://www.ncbi.nlm.nih.gov/pubmed/27498864 http://dx.doi.org/10.1016/j.celrep.2016.07.033 |
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