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Phospho-dependent Accumulation of GABA(B)Rs at Presynaptic Terminals after NMDAR Activation

Here, we uncover a mechanism for regulating the number of active presynaptic GABA(B) receptors (GABA(B)Rs) at nerve terminals, an important determinant of neurotransmitter release. We find that GABA(B)Rs gain access to axon terminals by lateral diffusion in the membrane. Their relative accumulation...

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Detalles Bibliográficos
Autores principales: Hannan, Saad, Gerrow, Kim, Triller, Antoine, Smart, Trevor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987283/
https://www.ncbi.nlm.nih.gov/pubmed/27498877
http://dx.doi.org/10.1016/j.celrep.2016.07.021