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ERK signaling promotes cell motility by inducing the localization of myosin 1E to lamellipodial tips

Signaling by extracellular signal–regulated kinase (ERK) plays an essential role in the induction of cell motility, but the precise mechanism underlying such regulation has remained elusive. We recently identified SH3P2 as a negative regulator of cell motility whose function is inhibited by p90 ribo...

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Detalles Bibliográficos
Autores principales: Tanimura, Susumu, Hashizume, Junya, Arichika, Naoya, Watanabe, Kazushi, Ohyama, Kaname, Takeda, Kohsuke, Kohno, Michiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987290/
https://www.ncbi.nlm.nih.gov/pubmed/27502487
http://dx.doi.org/10.1083/jcb.201503123