RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells

Collisions between replication and transcription machineries represent a significant source of genomic instability. RECQ5 DNA helicase binds to RNA-polymerase (RNAP) II during transcription elongation and suppresses transcription-associated genomic instability. Here, we show that RECQ5 also associat...

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Detalles Bibliográficos
Autores principales: Urban, Vaclav, Dobrovolna, Jana, Hühn, Daniela, Fryzelkova, Jana, Bartek, Jiri, Janscak, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987291/
https://www.ncbi.nlm.nih.gov/pubmed/27502483
http://dx.doi.org/10.1083/jcb.201507099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987291/
https://www.ncbi.nlm.nih.gov/pubmed/27502483
http://dx.doi.org/10.1083/jcb.201507099

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