TMX1 determines cancer cell metabolism as a thiol-based modulator of ER–mitochondria Ca(2+) flux

The flux of Ca(2+) from the endoplasmic reticulum (ER) to mitochondria regulates mitochondria metabolism. Within tumor tissue, mitochondria metabolism is frequently repressed, leading to chemotherapy resistance and increased growth of the tumor mass. Therefore, altered ER–mitochondria Ca(2+) flux co...

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Detalles Bibliográficos
Autores principales: Raturi, Arun, Gutiérrez, Tomás, Ortiz-Sandoval, Carolina, Ruangkittisakul, Araya, Herrera-Cruz, Maria Sol, Rockley, Jeremy P., Gesson, Kevin, Ourdev, Dimitar, Lou, Phing-How, Lucchinetti, Eliana, Tahbaz, Nasser, Zaugg, Michael, Baksh, Shairaz, Ballanyi, Klaus, Simmen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987292/
https://www.ncbi.nlm.nih.gov/pubmed/27502484
http://dx.doi.org/10.1083/jcb.201512077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987292/
https://www.ncbi.nlm.nih.gov/pubmed/27502484
http://dx.doi.org/10.1083/jcb.201512077

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