Atypical parkinsonism–associated retromer mutant alters endosomal sorting of specific cargo proteins

The retromer complex acts as a scaffold for endosomal protein complexes that sort integral membrane proteins to various cellular destinations. The retromer complex is a heterotrimer of VPS29, VPS35, and VPS26. Two of these paralogues, VPS26A and VPS26B, are expressed in humans. Retromer dysfunction...

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Detalles Bibliográficos
Autores principales: McMillan, Kirsty J., Gallon, Matthew, Jellett, Adam P., Clairfeuille, Thomas, Tilley, Frances C., McGough, Ian, Danson, Chris M., Heesom, Kate J., Wilkinson, Kevin A., Collins, Brett M., Cullen, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987296/
https://www.ncbi.nlm.nih.gov/pubmed/27528657
http://dx.doi.org/10.1083/jcb.201604057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987296/
https://www.ncbi.nlm.nih.gov/pubmed/27528657
http://dx.doi.org/10.1083/jcb.201604057

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