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Pharmacokinetic Bioequivalence of Two Inhaled Tiotropium Bromide Formulations in Healthy Volunteers

BACKGROUND AND OBJECTIVE: A novel tiotropium bromide monodose capsule dry powder inhaler (DPI) formulation and device have been developed. The formulation was based on a spray-dried matrix that enhances the aerosolizaton properties, allowing a less active tiotropium metered dose (13 µg/capsule) whil...

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Detalles Bibliográficos
Autores principales: Algorta, Jaime, Andrade, Laura, Medina, Marta, Kirkov, Valentin, Arsova, Sacha, Li, Fumin, Chi, Jingduan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987402/
https://www.ncbi.nlm.nih.gov/pubmed/27470430
http://dx.doi.org/10.1007/s40261-016-0441-8