Turning the respiratory flexibility of Mycobacterium tuberculosis against itself

The Mycobacterium tuberculosis (Mtb) electron transport chain (ETC) has received significant attention as a drug target, however its vulnerability may be affected by its flexibility in response to disruption. Here we determine the effect of the ETC inhibitors bedaquiline, Q203 and clofazimine on the...

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Detalles Bibliográficos
Autores principales: Lamprecht, Dirk A., Finin, Peter M., Rahman, Md. Aejazur, Cumming, Bridgette M., Russell, Shannon L., Jonnala, Surendranadha R., Adamson, John H., Steyn, Adrie J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987515/
https://www.ncbi.nlm.nih.gov/pubmed/27506290
http://dx.doi.org/10.1038/ncomms12393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987515/
https://www.ncbi.nlm.nih.gov/pubmed/27506290
http://dx.doi.org/10.1038/ncomms12393

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