Ordered chromatin changes and human X chromosome reactivation by cell fusion-mediated pluripotent reprogramming

Erasure of epigenetic memory is required to convert somatic cells towards pluripotency. Reactivation of the inactive X chromosome (Xi) has been used to model epigenetic reprogramming in mouse, but human studies are hampered by Xi epigenetic instability and difficulties in tracking partially reprogra...

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Detalles Bibliográficos
Autores principales: Cantone, Irene, Bagci, Hakan, Dormann, Dirk, Dharmalingam, Gopuraja, Nesterova, Tatyana, Brockdorff, Neil, Rougeulle, Claire, Vallot, Celine, Heard, Edith, Chaligne, Ronan, Merkenschlager, Matthias, Fisher, Amanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987517/
https://www.ncbi.nlm.nih.gov/pubmed/27507283
http://dx.doi.org/10.1038/ncomms12354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987517/
https://www.ncbi.nlm.nih.gov/pubmed/27507283
http://dx.doi.org/10.1038/ncomms12354

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