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Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling
Oocytes are arrested for long periods of time in the prophase of the first meiotic division (prophase I). As chromosome condensation poses significant constraints to gene expression, the mechanisms regulating transcriptional activity in the prophase I-arrested oocyte are still not entirely understoo...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987523/ https://www.ncbi.nlm.nih.gov/pubmed/27507044 http://dx.doi.org/10.1038/ncomms12331 |