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Early programming of the oocyte epigenome temporally controls late prophase I transcription and chromatin remodelling

Oocytes are arrested for long periods of time in the prophase of the first meiotic division (prophase I). As chromosome condensation poses significant constraints to gene expression, the mechanisms regulating transcriptional activity in the prophase I-arrested oocyte are still not entirely understoo...

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Detalles Bibliográficos
Autores principales: Navarro-Costa, Paulo, McCarthy, Alicia, Prudêncio, Pedro, Greer, Christina, Guilgur, Leonardo G., Becker, Jörg D., Secombe, Julie, Rangan, Prashanth, Martinho, Rui G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987523/
https://www.ncbi.nlm.nih.gov/pubmed/27507044
http://dx.doi.org/10.1038/ncomms12331