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Functional characterization of a monoclonal antibody epitope using a lambda phage display-deep sequencing platform

We have recently described a method, named PROFILER, for the identification of antigenic regions preferentially targeted by polyclonal antibody responses after vaccination. To test the ability of the technique to provide insights into the functional properties of monoclonal antibody (mAb) epitopes,...

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Detalles Bibliográficos
Autores principales: Domina, Maria, Lanza Cariccio, Veronica, Benfatto, Salvatore, Venza, Mario, Venza, Isabella, Borgogni, Erica, Castellino, Flora, Midiri, Angelina, Galbo, Roberta, Romeo, Letizia, Biondo, Carmelo, Masignani, Vega, Teti, Giuseppe, Felici, Franco, Beninati, Concetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987625/
https://www.ncbi.nlm.nih.gov/pubmed/27530334
http://dx.doi.org/10.1038/srep31458