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Functional characterization of a monoclonal antibody epitope using a lambda phage display-deep sequencing platform
We have recently described a method, named PROFILER, for the identification of antigenic regions preferentially targeted by polyclonal antibody responses after vaccination. To test the ability of the technique to provide insights into the functional properties of monoclonal antibody (mAb) epitopes,...
Autores principales: | Domina, Maria, Lanza Cariccio, Veronica, Benfatto, Salvatore, Venza, Mario, Venza, Isabella, Borgogni, Erica, Castellino, Flora, Midiri, Angelina, Galbo, Roberta, Romeo, Letizia, Biondo, Carmelo, Masignani, Vega, Teti, Giuseppe, Felici, Franco, Beninati, Concetta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987625/ https://www.ncbi.nlm.nih.gov/pubmed/27530334 http://dx.doi.org/10.1038/srep31458 |
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