DNMT1-PPARγ pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice

The DNA methyltransferase-mediated proinflammatory activation of macrophages is causally linked to the development of atherosclerosis (AS). However, the role of DNMT1, a DNA methylation maintenance enzyme, in macrophage polarization and AS development remains obscure. Here, we established transgenic...

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Detalles Bibliográficos
Autores principales: Yu, Jie, Qiu, Youzhu, Yang, Jie, Bian, Shizhu, Chen, Guozhu, Deng, Mengyang, Kang, Huali, Huang, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987643/
https://www.ncbi.nlm.nih.gov/pubmed/27530451
http://dx.doi.org/10.1038/srep30053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987643/
https://www.ncbi.nlm.nih.gov/pubmed/27530451
http://dx.doi.org/10.1038/srep30053

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