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DNMT1-PPARγ pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice

The DNA methyltransferase-mediated proinflammatory activation of macrophages is causally linked to the development of atherosclerosis (AS). However, the role of DNMT1, a DNA methylation maintenance enzyme, in macrophage polarization and AS development remains obscure. Here, we established transgenic...

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Detalles Bibliográficos
Autores principales:	Yu, Jie, Qiu, Youzhu, Yang, Jie, Bian, Shizhu, Chen, Guozhu, Deng, Mengyang, Kang, Huali, Huang, Lan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987643/ https://www.ncbi.nlm.nih.gov/pubmed/27530451 http://dx.doi.org/10.1038/srep30053

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