Diabetic Risk Factors Promote Islet Amyloid Polypeptide Misfolding by a Common, Membrane-mediated Mechanism

The current diabetes epidemic is associated with a diverse set of risk factors including obesity and exposure to plastics. Notably, significant elevations of negatively charged amphiphilic molecules are observed in obesity (e.g. free fatty acids and phosphatidic acid) and plastics exposure (monophth...

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Detalles Bibliográficos
Autores principales: Okada, Alan K., Teranishi, Kazuki, Isas, J. Mario, Bedrood, Sahar, Chow, Robert H., Langen, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987648/
https://www.ncbi.nlm.nih.gov/pubmed/27531121
http://dx.doi.org/10.1038/srep31094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987648/
https://www.ncbi.nlm.nih.gov/pubmed/27531121
http://dx.doi.org/10.1038/srep31094

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