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Analysis of Post-Traumatic Brain Injury Gene Expression Signature Reveals Tubulins, Nfe2l2, Nfkb, Cd44, and S100a4 as Treatment Targets

We aimed to define the chronically altered gene expression signature of traumatic brain injury (TBI-sig) to discover novel treatments to reverse pathologic gene expression or reinforce the expression of recovery-related genes. Genome-wide RNA-sequencing was performed at 3 months post-TBI induced by...

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Detalles Bibliográficos
Autores principales: Lipponen, Anssi, Paananen, Jussi, Puhakka, Noora, Pitkänen, Asla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987651/
https://www.ncbi.nlm.nih.gov/pubmed/27530814
http://dx.doi.org/10.1038/srep31570