The β-amyloid peptide compromises Reelin signaling in Alzheimer’s disease

Reelin is a signaling protein that plays a crucial role in synaptic function, which expression is influenced by β-amyloid (Aβ). We show that Reelin and Aβ oligomers co-immunoprecipitated in human brain extracts and were present in the same size-exclusion chromatography fractions. Aβ treatment of cel...

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Detalles Bibliográficos
Autores principales: Cuchillo-Ibañez, Inmaculada, Mata-Balaguer, Trinidad, Balmaceda, Valeria, Arranz, Juan José, Nimpf, Johannes, Sáez-Valero, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987719/
https://www.ncbi.nlm.nih.gov/pubmed/27531658
http://dx.doi.org/10.1038/srep31646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987719/
https://www.ncbi.nlm.nih.gov/pubmed/27531658
http://dx.doi.org/10.1038/srep31646

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