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Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour

Cancer cells migrate from the primary tumour into surrounding tissue in order to form metastasis. Cell migration is a highly complex process, which requires continuous remodelling and re-organization of the cytoskeleton and cell-matrix adhesions. Here, we aimed to identify genes controlling aspects...

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Detalles Bibliográficos
Autores principales: Fokkelman, Michiel, Balcıoğlu, Hayri E., Klip, Janna E., Yan, Kuan, Verbeek, Fons J., Danen, Erik H. J., van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987721/
https://www.ncbi.nlm.nih.gov/pubmed/27531518
http://dx.doi.org/10.1038/srep31707