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Cytoplasmic dynein binding, run length, and velocity are guided by long-range electrostatic interactions

Dyneins are important molecular motors involved in many essential biological processes, including cargo transport along microtubules, mitosis, and in cilia. Dynein motility involves the coupling of microtubule binding and unbinding to a change in the configuration of the linker domain induced by ATP...

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Detalles Bibliográficos
Autores principales: Li, Lin, Alper, Joshua, Alexov, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987762/
https://www.ncbi.nlm.nih.gov/pubmed/27531742
http://dx.doi.org/10.1038/srep31523