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The effect of purification of Ga-68-labeled exendin on in vivo distribution

BACKGROUND: Ga-labeled radiotracers are increasingly used for PET imaging. During the labeling procedure, formation of (68)Ga-colloid may occur. Upon i.v. injection, (68)Ga-colloid will accumulate rapidly in the liver, spleen, and bone marrow, resulting in reduced target-to-background ratios. In thi...

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Detalles Bibliográficos
Autores principales: Brom, Maarten, Franssen, Gerben M., Joosten, Lieke, Gotthardt, Martin, Boerman, Otto C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987764/
https://www.ncbi.nlm.nih.gov/pubmed/27518873
http://dx.doi.org/10.1186/s13550-016-0221-8