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Involvement of the FoxO1/MuRF1/Atrogin-1 Signaling Pathway in the Oxidative Stress-Induced Atrophy of Cultured Chronic Obstructive Pulmonary Disease Myotubes

Oxidative stress is thought to be one of the most important mechanisms implicated in the muscle wasting of chronic obstructive pulmonary disease (COPD) patients, but its role has never been demonstrated. We therefore assessed the effects of both pro-oxidant and antioxidant treatments on the oxidativ...

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Detalles Bibliográficos
Autores principales: Pomiès, Pascal, Blaquière, Marine, Maury, Jonathan, Mercier, Jacques, Gouzi, Fares, Hayot, Maurice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987766/
https://www.ncbi.nlm.nih.gov/pubmed/27526027
http://dx.doi.org/10.1371/journal.pone.0160092