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Galaxy7TM: flexible GPCR–ligand docking by structure refinement

G-protein-coupled receptors (GPCRs) play important physiological roles related to signal transduction and form a major group of drug targets. Prediction of GPCR–ligand complex structures has therefore important implications to drug discovery. With previously available servers, it was only possible t...

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Detalles Bibliográficos
Autores principales: Lee, Gyu Rie, Seok, Chaok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4987912/
https://www.ncbi.nlm.nih.gov/pubmed/27131365
http://dx.doi.org/10.1093/nar/gkw360